Ewout J Hoorn Selected Research

Hypovolemia

1/2022	Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.
1/2019	Recent developments in the management of acute and chronic hyponatremia.
1/2014	The sodium chloride cotransporter SLC12A3: new roles in sodium, potassium, and blood pressure regulation.
1/2013	Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.
6/2012	Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.

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Ewout J Hoorn Research Topics

Disease

39	Hypertension (High Blood Pressure) 04/2024 - 07/2005
21	Hyponatremia 11/2023 - 05/2004
20	Chronic Renal Insufficiency 10/2023 - 01/2013
12	Autosomal Dominant Polycystic Kidney (ADPKD) 12/2023 - 10/2016
10	Type 2 Diabetes Mellitus (MODY) 01/2023 - 07/2005
9	Hyperkalemia 10/2023 - 05/2012
9	Hypokalemia 03/2023 - 06/2006
8	Acidosis 10/2023 - 02/2015
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 07/2005
7	Kidney Diseases (Kidney Disease) 02/2024 - 06/2014
7	Albuminuria 02/2024 - 10/2017
7	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 12/2017
6	Disease Progression 12/2023 - 10/2016
6	Polycystic Kidney Diseases (Polycystic Kidney Disease) 11/2023 - 06/2014
5	Renal Insufficiency (Renal Failure) 11/2023 - 02/2015
5	Body Weight (Weight, Body) 03/2023 - 07/2015
5	Proteinuria 01/2023 - 12/2016
5	Hypovolemia 01/2022 - 06/2012
5	Hypernatremia 01/2022 - 05/2007
5	Inflammation (Inflammations) 12/2021 - 01/2011
5	Diabetes Mellitus 01/2020 - 03/2007
5	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 01/2019 - 08/2014
5	Inappropriate ADH Syndrome (SIADH) 03/2012 - 11/2009
4	Hyperaldosteronism (Conn Syndrome) 10/2023 - 01/2011
4	Neoplasms (Cancer) 01/2023 - 12/2007
4	Malaria 09/2016 - 05/2010
3	Hyperparathyroidism 11/2022 - 12/2018
3	Heart Failure 10/2021 - 07/2010
3	COVID-19 08/2021 - 01/2020
3	Nephrolithiasis 01/2020 - 08/2014
3	Kidney Calculi (Kidney Stone) 01/2019 - 05/2015
3	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 10/2011
3	Diabetic Nephropathies (Diabetic Nephropathy) 10/2017 - 07/2005
3	Acute Kidney Injury (Acute Renal Failure) 04/2017 - 06/2014
2	Alkalosis 10/2023 - 01/2021
2	Hypoparathyroidism 01/2023 - 07/2010
2	Dementia (Dementias) 01/2023 - 10/2017
2	Obesity 01/2023 - 01/2022
2	Cognitive Dysfunction 01/2023 - 12/2021
2	Secondary Hyperparathyroidism 12/2022 - 09/2020
2	Gitelman Syndrome 11/2022 - 06/2006
2	Stroke (Strokes) 11/2022 - 07/2005
2	Cysts 11/2022 - 01/2019
2	Potassium Deficiency 10/2022 - 12/2020
2	Hyperglycemia 01/2022 - 01/2020

Drug/Important Bio-Agent (IBA)

34	SodiumIBA 04/2024 - 05/2004
25	PotassiumIBA 04/2024 - 06/2006
24	SaltsIBA 10/2023 - 01/2008
13	DiureticsIBA 04/2024 - 12/2007
13	Vasopressins (Vasopressin)IBA 01/2021 - 05/2004
12	Biomarkers (Surrogate Marker)IBA 12/2023 - 05/2010
11	ReninIBA 01/2023 - 07/2014
10	ElectrolytesIBA 01/2023 - 01/2008
9	AldosteroneIBA 10/2023 - 06/2006
8	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2014
8	Dietary PotassiumIBA 10/2023 - 06/2006
8	Angiotensin IIIBA 01/2021 - 07/2005
8	MagnesiumIBA 12/2020 - 12/2007
7	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 01/2021 - 10/2011
6	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 01/2011
6	Glucose (Dextrose)FDA LinkGeneric 12/2022 - 05/2007
6	CreatinineIBA 11/2022 - 09/2016
6	AngiotensinsIBA 01/2022 - 10/2017
5	AngiotensinogenIBA 01/2022 - 10/2017
5	AcidsIBA 12/2021 - 12/2019
5	ThiazidesIBA 01/2021 - 06/2006
5	dirhodium tetraacetate (DRTA)IBA 01/2019 - 08/2014
4	Tolvaptan FDA Link 11/2022 - 03/2007
4	Antidiuretic Hormone Receptor AntagonistsIBA 01/2019 - 01/2008
4	Calcineurin InhibitorsIBA 06/2014 - 10/2011
4	Phosphotransferases (Kinase)IBA 01/2014 - 04/2009
3	Dinoprostone (PGE2)FDA Link 02/2024 - 01/2020
3	Phosphates (Orthophosphate)IBA 11/2023 - 12/2020
3	Sodium Chloride SymportersIBA 10/2023 - 10/2011
3	Epithelial Sodium ChannelsIBA 10/2023 - 01/2017
3	Sodium-Glucose Transport ProteinsIBA 10/2023 - 01/2020
3	Dietary SodiumIBA 10/2023 - 01/2020
3	Endothelin-1 (Endothelin 1)IBA 01/2023 - 11/2020
3	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 01/2023 - 05/2008
3	Parathyroid Hormone (Parathormone)IBA 01/2023 - 07/2010
3	CalciumIBA 11/2022 - 07/2010
3	Hemoglobins (Hemoglobin)IBA 11/2022 - 01/2015
3	AlbuminsIBA 01/2022 - 10/2017
3	Gliclazide (Diamicron)IBA 01/2022 - 01/2020
3	dapagliflozinIBA 01/2022 - 01/2020
3	Urea (Carbamide)FDA LinkGeneric 01/2022 - 01/2019
3	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 01/2020
3	Spironolactone (Aldactone)FDA LinkGeneric 01/2021 - 01/2011
3	Neprilysin (Neutral Endopeptidase)IBA 01/2020 - 07/2015
3	Tacrolimus (Prograf)FDA LinkGeneric 01/2020 - 10/2011
3	FludrocortisoneIBA 01/2019 - 05/2015
2	RNA (Ribonucleic Acid)IBA 12/2023 - 11/2022
2	Fibroblast Growth Factor-23IBA 11/2023 - 12/2021
2	Uric Acid (Urate)IBA 01/2022 - 01/2013

Therapy/Procedure

16	Therapeutics 12/2023 - 07/2005
9	Kidney Transplantation 12/2022 - 01/2011
4	Parathyroidectomy 12/2022 - 12/2018
4	Nephrectomy 01/2022 - 10/2017
2	Renal Replacement Therapy (Therapies, Renal Replacement) 11/2023 - 02/2015
2	Renal Dialysis (Hemodialysis) 01/2022 - 07/2013